Bio-production of lentiviral vectors

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专利权人:

Calimmune, Inc.

发明人:

Lee Chi-Lin,Bartlett Jeffrey S

申请号：

US201715802363

公开号：

US10138495(B2)

申请日:

2017.11.02

申请国别(地区):

美国

年份:

2018

代理人:

Charney IP Law LLC `Finetti Thomas

摘要：

The present disclosure provides a method of generating a stable producer cell line. The generation of stable producer cell lines, such as those provided in accordance with the present invention, increases the reproducibility and ease of creating high titer lentiviral stocks while easing biosafety concerns and the variation in expressed envelope proteins defines the tropism of the generated virus. The present disclosure also provides for a novel lentiviral transfer vector plasmid.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/