TSO, J. YUN,TSURUSHITA, NAOYA,LANDOLFI, NICHOLAS F.,KUMAR, SHANKAR
申请号:
EP11766761
公开号:
EP2560994A4
申请日:
2011.04.07
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The invention provides monoclonal antibodies that specifically bind to CD122, which is one component of receptors for IL-2 and IL-15. The monoclonal antibodies have the capacity for substantial inhibition of both IL-2 and IL-15 mediated functions by inhibiting binding of these cytokines to their receptors. The monoclonal antibodies can be used for inhibiting undesired immune responses or treatment of cancer, among other applications.