Provided are a solid pharmaceutical dosage form of a PARP inhibitor, and an application of the solid pharmaceutical dosage form of the PARP inhibitor. Specifically, provided is a solid dispersion powder, including amorphous 5-fluoro-1-(4-fluoro-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)quinazoline-2,4(1H,3H)-dione and a polymer, the amount of the polymer being approximately 50% by weight to approximately 80% by weight, at least 10% by weight of the 5-fluoro-1-(4-fluoro-3-(4-(pyrimidin-2-yl)piperazine-1-carbonyl)benzyl)quinazoline-2,4(1H,3H)-dione being in a crystalline form. Also provided is a preparation method for the solid dispersion powder, a pharmaceutical composition including the solid dispersion powder, and a use of the pharmaceutical composition to treat diseases caused by PARP activity abnormalities.
