具有EP1受體活性之經取代的三環化合物(二)农业专利-农业专业知识服务系统

专利权人:: DRACONIS PHARMA, S.L.;ALMIRALL;LABORATORIOS DEL DR. ESTEVE, S. A.;ALMIRALL, S. A.; S. A.

发明人:: AGUILAR, NURIA,阿古拉　努里雅,FERNANDEZ, JOAN CARLES,法南德兹　琼　普约尔,法南德茲　瓊　普約爾,TERRICABRAS, EMMA,得里卡不拉斯　艾玛,得里卡不拉斯　艾瑪,CARCELLER GONZALEZ, ELENA,卡拉西列　康那列兹　爱莲那,卡拉西列　康那列茲　愛蓮那,SALAS SOLANA, JORDI,萨拉斯　索那拉　尤维,薩,阿古拉努里雅,法南德兹琼普约尔,法南德茲瓊普約爾,得里卡不拉斯艾玛,得里卡不拉斯艾瑪,卡拉西列康那列兹爱莲那,卡拉西列康那列茲愛蓮那,萨拉斯索那拉尤维

摘要：: The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP1 receptor as well as to pharmaceutical compositions comprising them.本發明屬於EP1受體配位體之領域。更精確地說本發明係關於對EP1受體具有高親和力與選擇性的通式(I)化合物。本發明亦關於該等化合物的製備方法與其作為藥劑用於治療及/或預防經EP1受體調控之疾病或病症的用途，以及包含該等化合物之醫藥組合物。