ANNA N. MORAITIS,GILLES BERNARD TREMBLAY,MARIO FILION,TRAIAN SULEA
申请号：
BR112013025198
公开号：
BR112013025198A2
申请日:
2012.03.28
申请国别(地区):
BR
年份:
2018
代理人:
摘要：
Novel antibodies and antigen binding fragments that specifically bind to KAAG1 and which may be used in the treatment, detection and diagnosis of cancer comprising KAAG1 -expressing cells are disclosed herein. Cells expressing the antibodies and antigen binding fragments as well as methods of detecting and treating cancer using the antibodies and fragments are also disclosed. Cancer indications which may benefit from such treatment or detection include ovarian cancer, renal cancer, lung cancer, colorectal cancer, breast cancer, brain cancer, and prostate cancer, as well as melanomas.
