Disclosed in an embodiment herein is a well plate system including a well plate device, including three plates disposed above one another. The two top plates include wells disposed therein which are in fluid communication with one another, and which when the device is in a resting position, the second plate rests on top of the third plate to create a fluid sealed well. The third plate includes fluid drainage openings, such that when the system is in an activated position, the plates are moved such that the fluid within the wells exits through these openings. The system can be fully automated, and can include one or more motors to control movement of the plates. The system can also operate manually with a hinge connected to the plates.