BAI ,HUA,HONG ,JIAN,CAI ,LIFENG,WEI ,HEGENG,LIU ,XIAOYU,ZHENG, XIAOHE
申请号：
IN9941DEN2014
公开号：
IN9941DEN2014A
申请日:
2014.11.24
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Disclosed are a 4 -((substituted phenyl) difluoromethyl) phenoxy carboxylic acid derivative , and preparation method and uses thereof. More particularly , the present invention relates to a compound having a structure as represented by formula I and defined in the description. The compound of the present invention can be used as a PPAR agonist, and demonstrates a relatively strong effect on reducing the levels of total cholesterol (TC), triglyceride (TG), and low density lipoprotein cholesterol (LDL- C) in plasma. Therefore, the compound of the present invention can be used to prepare drugs for treating or preventing hyperlipemia, or cardiovascular and cerebrovascular diseases caused by hyperlipemia , such as diabetes , atherosclerosis, stroke , and coronary heart disease. The present invention also relates to a novel intermediate compound for preparing the compound as represented by formula I , and preparation method thereof.
