The present invention provides the methods of the 227Th for the mixture purification complexing from the 227Th comprising complexing and 223Ra (complexing or in the solution), the described method includes: i) preparing the first solution, it includes the mixtures of the 227Th ions of the complexing in the first aqueous buffer and 223Ra ions Ii) first solution is loaded into separation material Iii) from the 227Th of separation material elution complexing, the second solution of the 227Th comprising complexing is thus generated Iv) separation material optionally is rinsed using the first Aqueous wash medium Invention additionally provides purified 227Th solution, drug products and its purposes in treatment diseases such as cancer and the kits for generating such product.