Ernest G. Schutt;Thomas E. Tarara;Alexey Kabalnov;Jeffrey G. Weers;Luis A. Dellamary
发明人:
Thomas E. Tarara,Jeffrey G. Weers,Alexey Kabalnov,Ernest G. Schutt,Luis A. Dellamary
申请号：
US12774540
公开号：
US09554993B2
申请日:
2010.05.05
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A pulmonary delivery medicament comprises a plurality of particulates, the particulates comprising a structural matrix and a water insoluble and/or crystalline active agent. The particulates have a geometric diameter of 0.5 to 50 μm. The water insoluble active agent can be a fungicide, antibiotic, budesonide. A method of making the medicament comprises forming a liquid feedstock, and forming a feedstock suspension by suspending in the liquid feedstock, the active agent and an excipient capable of forming a structural matrix, such as a phospholipid. The feedstock suspension is spray dried to produce the particulates.
