Contrast agents endowed with high relaxivity

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专利权人:

Silvio Aime

发明人:

Silvio Aime,Matteo Galli,Luciano Lattuada,Pierfrancesco Morosini,Fulvio Uggeri,Kondareddiar Ramalingam

申请号：

US11630600

公开号：

US08540966B2

申请日:

2005.06.28

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The present invention relates to a novel class of paramagnetic ion-based contrast agents of formula (I), wherein a chelating backbone moiety is highly functionalized by the presence of one or more polyhydroxylated chain, that show a pharmacokinetic profile analogous to that of the commonly used T1-general extravascular agents (NSA) but are further characterized by a higher relaxivity.

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