A surgical robot system includes a manipulator for a surgical instrument intended for use in one single operation, a control unit for controlling the manipulator, and a read and write device for reading and storing data of a data memory. The read and write device is configured to read out first data with first information on the surgical instrument from the data memory and to transmit them to the control unit when the surgical instrument is coupled with the robot system. The control unit checks whether at least the one compatibility criterion meets at least one compatibility condition stored in the control unit in a preset manner based on the second information. The control unit approves the surgical instrument for use by the surgical robot system only when the compatibility criterion meets the at least one compatibility condition stored in a preset manner.