Ji-In Kim,Kellen L. Olszewski,Anthony M. Barsotti,Masha V. Poyurovsky,Kevin G. Liu,Koi Morris,Xuemei Yu
申请号:
US16608233
公开号:
US20200046702A1
申请日:
2018.04.27
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This invention provides methods of treating inflammatory conditions and autoimmune diseases in a mammal, comprising administering to the mammalian subject in need thereof a therapeutically effective amount of a compound, or pro-drug thereof, or pharmaceutically acceptable salt or ester of said compound or pro-drug, wherein the compound is an inhibitor of glucose uptake. In particular aspects, the present invention provides a method of treating inflammatory conditions and autoimmune diseases in a mammal, and preferably a human, in which the glucose uptake inhibitor modulates the glucose transport of GLUT1 and GLUT3.