#$%^&*AU2019250217A120191107.pdf#####ABSTRACT A medical delivery device comprising: a barrel containing at least one therapeutic； a plunger rod having a distal end inserted within the barrel； a stopper attached to the distal end of the plunger rod and contacting at least a portion of the inner surface of the barrel, the stopper comprising an elastomeric body, one or more fluoropolymer layers, and two or more ribs having a sealing surface and being positioned on the one or more fluoropolymer layers； wherein a contact width between at least one of said two or more ribs and a portion of the inner surface of the barrel measured at a compressibility of greater than about 7.9% of the stopper is less than about 1.0 mm. FIG.1 -4511798906_1 (GHMatters)P109022.AU.12/6 100 140 130 125 FIG 2 100 >；4 125 150145 130 FIG. 3
