A system for managing an inventory of process control devices in a process plant includes a computer workstation, a database storing instrument specification data for one or more process control devices used for controlling a process performed in the process plant environment, a wireless gateway adapted to wirelessly communicate with wireless enabled process control devices in the process plant environment, a communication bus interconnecting the wireless gateway, the computer workstation, and the database, an inventory control application executed by the computer workstation. The inventory control application is adapted to interrogate a received process control device via the wireless gateway to receive device data from the received process control device identifying and describing the received process control device. The inventory control application is further adapted to access the database to retrieve instrument specification data for the received process control device and compare the received device data to the retrieved instrument specification data. The inventory control application ensures that the received process control device corresponds to the instrument specification data.