ACADEMIA SINICA;WONG, CHI-HUEY;FANG, JIM-MIN;SHIE, JIUN-JIE
发明人:
WONG, CHI-HUEY,FANG, JIM-MIN,SHIE, JIUN-JIE
申请号：
CA2883168
公开号：
CA2883168A1
申请日:
2013.08.21
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Provided are benzocyclooctyne compounds of formula (I). These compounds undergo strain-promoted azide-alkyne cyclo additions (SPAAC) without presence of toxic metal catalysts. The provided compounds are useful for diagnosis and imaging of azide-containing molecules. Methods for detection and imaging biomolecules using compounds of the present disclosure are disclosed.
