COSTA-MATTIOLI, Mauro,BUFFINGTON, Shelly Alexandra
申请号:
EP17783343
公开号:
EP3442547A4
申请日:
2017.04.15
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
Embodiments of the disclosure concern methods and compositions related to manipulation of the microbiome in an individual having at least one social behavior deficit. In particular embodiments, an individual has at least one social behavior deficit and was born from a mother who during pregnancy was obese, overweight, or on a high-fat diet during pregnancy or carries mutations associated with neurodevelopmental disorders. In specific embodiments, the individual having at least one social behavior deficit is provided an effective amount of Lactobacillus reuteri for the improvement of at least one symptom of a social behavior deficit.