CYCLE ADENOSINE MONOPHOSPHATE-INCOMPETENT ADENYLYL CYCLASE AND COMPOSITIONS AND METHODS FOR TREATING HEART FAILURE AND INCREASING CARDIAC FUNCTION

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专利权人:

发明人:

申请号：

EP14808138.3

公开号：

EP3004343A4

申请日:

2014.06.04

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

The invention provides methods for treating, ameliorating or protecting (preventing) an individual or a patient having or at risk of having heart disease or heart failure, or decreased cardiac function, comprising: providing a cyclic adenosine monophosphate-incompetent (cAMP-incompetent) adenylyl cyclase type 6 (AC6) protein or polypeptide (also called &ldquoan AC6mut&rdquo), or an AC6mut-encoding nucleic acid or a gene operatively linked to a transcriptional regulatory sequence.

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