TEVA WOMEN&rsquoS HEALTH INC.;TEVA WOMEN’S HEALTH INC.
发明人:
AHMED SALAH U,TSAO JIAXIANG,MAHASHABDE ANU,HARRISON DIANE D.
申请号:
NZ61126809
公开号:
NZ611268A
申请日:
2009.02.03
申请国别(地区):
NZ
年份:
2015
代理人:
摘要:
Disclosed herein is the use of (a) a therapeutically effective amount of progesterone; (b) a polysiloxane eleastomer; and (c) a pharmaceutically acceptable hydrocarbon or glycerol ester of a fatty acid for the manufacture of a medicament for the treatment of an infertile woman with progesterone deficiency, wherein said medicament is a monolithic intravaginal ring comprising said therapeutically effective amount of progesterone, said polysiloxane elastomer and said pharmaceutically acceptable hydrocarbon or glycerol ester of a fatty acid, wherein the intravaginal ring is adapted for administration of about 10 mg to about 20 mg progesterone per day at a steady state for up to 18 days after administration to the subject; and wherein the polysiloxane elastomer is present in a concentration of about 55% to about 90% by total weight of the ring.