James John Crawford,Aleksandr Kolesnikov,Jianwen A. Feng
申请号:
US16221274
公开号:
US10550117B2
申请日:
2018.12.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention relates to compounds of formula (I):wherein Q, A1, A2, A3, A5, A6, A7, A8, R4a, R4b and R5 are as described herein. Compounds of formula (I) and pharmaceutical compositions thereof are useful in the treatment of diseases and disorders in which undesired or over-activation of NF-kB signaling is observed.