Process for obtaining ketamine enantiomers and their pharmaceutically acceptable salts

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专利权人:

CRISTALIA PRODUTOS QUIMICOS FARMACEUTICOS LTDA.

发明人:

VALTER FREIRE TORRES RUSSO,ELISA MANNOCHIO DE SOUZA RUSSO

申请号：

BR0002693

公开号：

BR0002693B1

申请日:

2000.06.19

申请国别(地区):

BR

年份:

2013

代理人:

摘要：

The present invention describes a new process for obtainment of the cetamine enantiomers, from the racemic cetamine resolutions with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers. The resolution agent is employed in special concentration conditions, which provides stability, reproducibility and high enantiomeric purity to the precipitated diasteromer salt, making feasible the industrial production of the S-cetamine and its pharmaceutically acceptable salts.

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