KHANNANOV TIMUR SHAMILOVICH,Ханнанов Тимур Шамилович,ANISIMOV ALEKSANDR NIKOLAEVICH,Анисимов Александр Николаевич,AVDONINA NINA NIKOLAEVNA,Авдонина Нина Николаевна,KAMAEVA SVETLANA SERGEEVNA,Камаева С
申请号：
RU2013127704/15
公开号：
RU0002537169C1
申请日:
2013.06.18
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
FIELD: medicine, pharmaceutics.SUBSTANCE: invention refers to pharmaceutical industry and medicine, namely to manufacturing drug preparations for treating allergic diseases, such as allergic rhinitis and urticaria. According to the first version, the pharmaceutical composition contains an active substance that is desloratadine, and additives, including citric acid, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, starch, lactose, magnesium stearate, and talc. According to the second version, the pharmaceutical composition contains an active substance that is desloratadine, and additives, including Pearlitol 100SD-Mannitol, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, starch, magnesium stearate, and talc. According to the third version, the pharmaceutical composition contains an active substance that is desloratadine, and additives, including sodium carboxymethyl starch, microcrystalline cellulose, colloidal silicone dioxide, and sodium sodium stearyl fumarate. According to the fourth version, the pharmaceutical composition contains an active substance that is desloratadine, and additives, including sodium carboxymethyl starch, microcrystalline cellulose, Pearlitol 100SD-Mannitol, magnesium stearate, and talc. The pharmaceutical composition is presented in the form of a film-coated tablet.EFFECT: pharmaceutical composition according to the invention is storage-stable and releases the active substance quickly in the gastrointestinal tract.10 cl, 9 tbl, 20 exИзобретение относится к фармацевтической промышленности и медицине, а именно к производству лекарственных препаратов для лечения аллергических заболеваний, таких как аллергический ринит, крапивница. Фармацевтическая композиция согласно первому варианту включает активное вещество - дезлоратадин и вспомогательные вещества - лимонную кислоту, кальция гидрофосфата дигидрат, микрокристаллическую целлюлозу, крахмал, лактозу, стеарат магния, тальк. Фармацевтическая композиция согласно
