Composition for inhibition of multidrug resistance containing an extract of Dictamnus dasycarpus Turcz.

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专利权人:

경희대학교 산학협력단;UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY

发明人:

고성규,설현철,임희선,최형심,KO, SEONG GYU,SEOL, HYUN CHUL,YIM, HEE SUN,CHOI, HYEONG SIM

申请号：

KR1020110041850

公开号：

KR1020120124142A

申请日:

2011.05.03

申请国别(地区):

KR

年份:

2012

代理人:

摘要：

PURPOSE: A pharmaceutical composition containing Dictamnus dasycarpus Turcz. extract is provided to overcome anticancer agent resistance and to be used as a composition for suppressing multidrug resistance. CONSTITUTION: A pharmaceutical composition for suppressing multidrug resistance for an anticancer agent contains 0.001-50 wt% of Dictamnus dasycarpus Turcz. extract as an active ingredient. The extract is prepared using water, low carbon number alcohol of 1-4 carbon atoms, or a mixture solvent thereof. The multi-drug resistance is resistance by P-glycoprotein. A pharmaceutical composition for anticancer contains the extract as an active ingredient. A sitological composition for anticancer aid contains the extract as an active ingredient.본 발명은 다중약물내성(multidrug resistance, MDR) 억제능이 매우 뛰어난 백선피 추출물을 유효성분으로 포함하는 다중약물내성 억제용 약학적 조성물을 제공한다. 본 발명의 조성물은 항암제에 내성을 나타내는 다중약물 내성 세포에서 보이는 항암제 내성을 극복할 수 있어, 약학적으로 유용한 다중약물내성 억제용 조성물 및 항암보조제로 사용될 수 있다.

来源网站：

中国工程科技知识中心

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