Neil Westlund,Jason Hill,Mark A. Ashwell,Nivedita Namdev,Jianqiang Wang,Syed Ali
申请号:
US12664345
公开号:
US08513292B2
申请日:
2008.06.19
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to pyrrolidine-2,5-dione compounds, and methods of preparation of these compounds. The present invention also relates to pharmaceutical compositions comprising pyrrolidine-2,5-dione compounds. The present invention provides methods of treating a cell proliferative disorder, such as a cancer, by administering to a subject in need thereof a therapeutically effective amount of a compound or pyrrolidine-2,5-dione compound of the present invention. (Ia) (Ib) (IIa) (IIIb) Where U is independently selected from: (I) or (II)where U is independently selected from: