INSERM (Institut National de la Sante et de la Recherche Medicale);Universite de Paris—Sud;Commissariat a l'Energie Atomique et aux Energies Alternatives;Centre National de la Recherche Scientifique (CNRS);Universite Paris Descartes
The present invention relates to a vector comprising a nucleic acid sequence that encodes the APP protein and/or the PS1 protein or variants thereof. The invention also relates to a method for inducing the Alzheimer's disease in an animal using the vector of the invention and to animal model having the Alzheimer's disease obtained by said method.