The invention relates to compositions and methods for treating allergy, e.g., peanut allergy, in patients. The methods involve administering glucopyranosyl lipid adjuvant (GLA) and peanut allergen(s) to the patient via a sublingual route.本發明關於治療病患過敏(例如花生過敏)之組成物及方法。該方法包含將吡喃葡萄糖基脂質佐劑(GLA)及花生過敏原經由舌下路徑投藥給病患。