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PROCEDURE FOR PREVENTING RESPONSE TO DISEASES OF PHARMACOLOGICAL CHAPERONE TREATMENT
专利权人:
Inc.;Amicus Therapeutics
发明人:
Benjamin, Elfrida,Do, Hung V,Wu, Xiaoyang,FLANAGAN, John,WUSTMAN, Brandon
申请号:
DK15162630
公开号:
DK2946785T3
申请日:
2009.02.12
申请国别(地区):
DK
年份:
2019
代理人:
摘要:
A method of compiling a treatment reference table that indicates the responsiveness of one or more specific mutations of ±-Gal A to a specific pharmacological chaperone, the method comprising: analysing in vitro the response to the specific pharmacological chaperone in a host cell that has been transformed with a nucleic acid vector that encodes a first mutant ±-Gal A and compiling a table listing responsive and non-responsive mutant forms of ±-Gal A. The specific pharmacological chaperone is 1-deoxygalactonojirimycin or a pharmaceutically salt or ester and the first cell is HEK-293 MSR cell.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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