Pingda Ren;Katrina Chan;Troy Edward Wilson;Yi Liu;Liansheng Li
发明人:
Yi Liu,Pingda Ren,Liansheng Li,Katrina Chan,Troy Edward Wilson
申请号:
US12920970
公开号:
US08637542B2
申请日:
2009.03.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention provides chemical entities or compounds and pharmaceutical compositions thereof that are capable of modulating lipid kinases such PB kinases, tryosine kinases and protein kinases such as mTOR. Also provided in the present invention are methods of using these compositions to modulate these kinases especially for therapeutic applications.