CATHELICIDIN LL-37及其衍生物在傷口癒合中的用途

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专利权人:

Lipopeptide AB

发明人:

STHLE-BCKDAHL, Mona -,HEILBORN, Johan,CARLSSON, Anders,BOGENTOFT, Conny,莫娜.斯塔爾-巴克達爾,約翰.海爾博恩,安德斯.卡爾森,康尼.博根托夫特

申请号：

HK16105830.5

公开号：

HK1217661A

申请日:

2016.05.23

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

Use of the antimicrobial cathelicidin peptide II-37, N-terminal fragments of LL-37 or extended sequences of LL-37 having 1-3 amino acids in the C-terminal end, for stimulating proliferation of epithelial and stromal cells and thereby healing of wounds, such as chronic ulcers. The cytotoxic effect of LL-37 may be reduced by including a bilayer-forming polar lipid, especially a digalactosyldiacylglycerol, in pharmaceutical compositions and growth media comprising LL-37.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/