ГРАНДИ Гвидо (IT),ГРИФАНТИНИ Рената Мария (IT),ФИНКО Оретта (IT)
申请号：
RU2011140508/10
公开号：
RU2011140508A
申请日:
2010.03.08
申请国别(地区):
RU
年份:
2013
代理人:
摘要：
1. A protein containing any amino acid sequence from SEQ ID NO: 2, SEQ ID NO: 4, SEQ ID NO: 6, SEQ ID NO: 8, SEQ ID NO: 10, SEQ ID NO: 12, SEQ ID NO: 14 , SEQ ID NO: 16, SEQ ID NO: 18, SEQ ID NO: 40, SEQ ID NO: 42, SEQ ID NO: 44, SEQ ID NO: 46, SEQ ID NO: 48, SEQ ID NO: 50, SEQ ID NO: 52, SEQ ID NO: 54, SEQ ID NO: 136 or SEQ ID NO: 140, for use in therapy or diagnosis. 2. A protein having 50% or more sequence identity with the protein of claim 1.3. A protein containing a fragment of the amino acid sequence according to claim 1 or 2.4. The protein of claim 3, wherein the fragment contains at least 8 consecutive amino acids from the amino acid sequence of claim 1 or 2.5. A protein binding antibody according to any one of claims 1 to 4 for use in therapy or diagnosis. A nucleic acid molecule encoding a protein or antibody according to any one of claims 1 to 5, for use in therapy or diagnosis. The nucleic acid molecule according to claim 6, containing any nucleotide sequence from SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 7, SEQ ID NO: 9, SEQ ID NO: 11, SEQ ID NO: 13, SEQ ID NO: 15, SEQ ID NO: 17, SEQ ID NO: 39, SEQ ID NO: 41, SEQ ID NO: 43, SEQ ID NO: 45, SEQ ID NO: 47, SEQ ID NO : 49, SEQ ID NO: 51, SEQ ID NO: 53, SEQ ID NO: 135 or SEQ ID NO: 139.8. A nucleic acid molecule containing a fragment of any nucleotide sequence from SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 5, SEQ ID NO: 7, SEQ ID NO: 9, SEQ ID NO: 11, SEQ ID NO: 13, SEQ ID NO: 15, SEQ ID NO: 17, SEQ ID NO: 39, SEQ ID NO: 41, SEQ ID NO: 43 or SEQ ID NO: 45, SEQ ID NO: 47, SEQ ID NO: 49, SEQ ID NO: 51, SEQ ID NO: 53, SEQ ID NO: 135 or SEQ ID NO: 139.9. A nucleic acid molecule containing a nucleotide sequence complementary to a nucleic acid molecule according to any one of claims 6 to 8.10. A nucleic acid molecule containing nucleotide sequences having 50% or more sequence identity with a nucleic acid molecule according to any one of claims 6 to 9.11. Nucleic acid molecule, c1. Белок, содержащий любую а
