A method of making an ultrasound catheter for disrupting occlusions in blood vessels, the method comprising: either:placing a catheter body over a mandrel, wherein the mandrel includes at least one bend for forming a corresponding bend in the catheter body; heating the catheter body; removing the catheter body from the mandrel; or: forming a catheter body over a mandrel, wherein the mandrel includes at least one bend for forming a corresponding bend in the catheter body; separating the catheter body from the mandrel; the method further comprising: inserting an ultrasound transmission member into a lumen of the catheter body, wherein inserting the ultrasound transmission member reduces an angle of the at least one bend in the catheter body.