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Interleukin-1 and tumor necrosis factor-a modulators; syntheses of such modulators and methods of using such modulators
专利权人:
Inc.;Nereus Pharmaceuticals;Nereus Pharmaceuticals, Inc.;The Regents of the University of California
发明人:
Macherla, Venkat Rami Reddy,Chao, Ta-Hsiang,Theodorakis, Emmanuel A.,Suh, Young Ger,Palladino, Michael A.
申请号:
AU2006276274
公开号:
AU2006276274B2
申请日:
2006.07.14
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Compounds are disclosed that have the chemical structure of Formula (II), (IIA)and (IIB) and their prodrug esters and acid-addition salts, and that are usefulas Interleukin-1 and Tumor Necrosis Factor-a modulators, and thus are usefulin the treatment of various diseases, wherein the R groups are defined in the claims.
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