USTAV MAKROMOLEKULARNI CHEMIE AV CR, V.V.I.;USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR, V.V.I.;USTAV ORGANICKE CHEMIE A BIOCHEMIE AV CR; V.V.I.;UNIVERZITA KARLOVA V PRAZE, PRIRODOVEDECKA FAKULTA
Macromolecular water-soluble conjugates based on synthetic copolymers to which at least one affinity tag, at least one imaging probe, and at least one targeting ligand are bound via covalent bonds. The macromolecular conjugate may be used in identification, visualization, quantification or isolation of proteins and/or cells. The targeting ligand may be attached to the synthetic copolymer via a flexible linker.