Antigen binding proteins, such as antibodies, that interact with Epidermal Growth Factor Receptor (EGFR) are described. Methods of treating cancers and other diseases by administering a pharmaceutically effective amount of an antigen binding protein to EGFR are also described.本發明論述與表皮生長因子受體(EGFR)相互作用之抗原結合蛋白(諸如抗體)。本發明亦論述藉由投與醫藥有效量之EGFR抗原結合蛋白治療癌症及其他疾病之方法。