An apparatus for driving a two-dimensional (2D) transducer array, a medical imaging system, and a method of driving a 2D transducer array are provided. The apparatus for driving a two-dimensional (2D) transducer array including one or more transducers includes one or more drivers configured to respectively drive the transducers, each of the drivers including a register, a comparator, a pulse frequency setter, a multi-pulse controller, a transmission signal generator, a signal transceiver, a transmission and reception switch, and a reception signal amplifier, and a driving controller configured to control the drivers.2차원 트랜스듀서-어레이를 구동시키는 장치, 의료영상시스템 및 2차원 트랜스듀서-어레이를 구동시키는 방법에 따르면, 2차원 트랜스듀서-어레이를 구동시키는 구동장치는 2차원 트랜스듀서-어레이에 포함된 트랜스듀서들 각각을 구동시키는 복수의 구동부들, 및 복수의 구동부들을 제어하는 구동 제어부를 포함한다.
