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Antagonists to IL-6 to raise albumin and/or lower CRP
专利权人:
发明人:
Jeffrey T. L. Smith
申请号:
US14968098
公开号:
US10040851B2
申请日:
2015.12.14
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention is directed to therapeutic methods using IL-6 antagonists such as antibodies and fragments thereof having binding specificity for IL-6 to improve survivability or quality of life of a patient in need thereof. In preferred embodiments these patients will comprise those exhibiting (or at risk of developing) an elevated serum C-reactive protein level or a reduced serum albumin level prior to treatment. In another preferred embodiment, the patients Glasgow Prognostic Score will be increased and survivability will preferably be improved.
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