Susanne I. Wells,Kenneth D.R. Setchell,Lindsey Romick-Rosendale,Wujuan Zhang,Xueheng Zhao
申请号：
US15358620
公开号：
US20170100462A1
申请日:
2016.11.22
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Markers for genomic instability in Fanconi Anemia (FA) and other pathologies for therapeutic and diagnostic uses. In one embodiment, glycosphingolipid metabolism is altered in the FA deficient squamous cell carcinoma (SCC) cells, based on analysis of a metabolomics/lipidomics platform. The data indicated ganglioside metabolism was important in FA patients susceptibility to SCC progression.
