Nazareno Paolocci,Ning Feng,Carlo G. Tocchetti,Cyrus Takahashi,Bruce Carter
申请号：
US15762238
公开号：
US20180271931A1
申请日:
2016.09.22
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides 75 kD transmembrane neurotrophin receptor (p75NTR) antagonists and their use in prevention and treatment of loss of function, and adverse remodeling, in cardiac tissues subject to acute or chronic hemodynamic stress. Uses of the antagonists with or without additional cardiotropic agents for improving contractility and for treatment of congestive heart failure are also provided.
