The human CC chemokine receptor 4 (below, it names also CCR4) the gene recombination antibody which is joined uniquely and, the gene recombination antibody for medicine, and CCR4 which at least include the medicine of 1 types, at least jointly using with the medicine of 1 types, the medicine in order to prescribe is required. According to this invention, the gene recombination antibody which is joined to CCR4 uniquely and, the gene recombination antibody for medicine, and CCR4 which at least include the medicine of 1 types, jointly using with the medicine of 1 types at least, the medicine in order to prescribe is offered.ヒトCCケモカイン受容体4(以下、CCR4とも称す)に特異的に結合する遺伝子組換え抗体と、少なくとも1種類の薬剤を含む医薬、およびCCR4に対する遺伝子組換え抗体を、少なくとも1種類の薬剤とを併用して投与するための医薬が求められている。本発明によれば、CCR4に特異的に結合する遺伝子組換え抗体と、少なくとも1種類の薬剤を含む医薬、およびCCR4に対する遺伝子組換え抗体を、少なくとも1種類の薬剤とを併用して投与するための医薬が提供される。
