Endoscopic medical devices for removing tissue include: (a) a forceps with an elongate shaft slidably residing in a first working channel of an endoscope and having an externally accessible forceps control; and (b) a snare with an elongate shaft comprising a wire loop slidably residing in the first working channel of the endoscope, the snare having an externally accessible snare control. The forceps and snare shafts reside adjacent to and substantially parallel to each other inside the first working channel of the endoscope, one above or to the side of the other. In use, the forceps and snare cooperate so that the forceps control directs the forceps to extend out of the endoscopic first working channel and grasp target tissue, then the snare control directs the snare loop to exit the working channel while the snare loop encircles the forceps shaft and extends a distance sufficient to surround the forceps.