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human protein fragment fusion proteins to create ordinary multimerized fc immunoglobulin compositions with enhanced complement ratio
专利权人:
GLIKNIK INC
发明人:
DAVID S. BLOCK,HENRIK OLSEN
申请号:
BR112017028550
公开号:
BR112017028550A2
申请日:
2016.07.22
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
The present invention relates to a series of fully recombinant multimerized forms of fc immunoglobulin thus presenting polyvalent fc immunoglobulin to immune cell receptors. Fusion proteins exist as homonymous and highly ordered multimeric fractions called stradomers. The invention relates to multimerization enhancing and preferentially binding stradomers which are useful in the treatment and prevention of diseases.a presente invenção refere-se a uma série de formas multimerizadas totalmente recombinantes de imunoglobulina fc que apresentam assim a imunoglobulina fc polivalente a receptores de células imunes. as proteínas de fusão existem como frações homônimas e altamente ordenadas multiméricas, denominadas stradomers. a invenção refere-se a stradomers que aumentam a multimerização e se ligam preferencialmente para complementar e que são úteis no tratamento e prevenção de doenças.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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