The bright Should being related on Qi System Prepare method of pyridone Class derivative, and its Medical Drug of this Hair is used. For having a Body; this Hair is bright to be related to a Seed and lead to pyridone Class derivative shown in formula (I) and its can Drug Which; its System Prepare method and its Men are the purposes that Treatment Elixirs is controlled as cancer as MEK inhibition Elixirs spy Do, each substituent group in formula of (I) determine Righteousness With illustrate in Books to determine Righteousness identical.本發明涉及吡啶酮類衍生物、其製備方法及其在醫藥上的應用。具體而言,本發明涉及一種通式(I)所示吡啶酮類衍生物及其可藥用鹽,其製備方法以及它們作爲MEK抑制劑特別是作爲癌症治療劑的用途,其中通式(I)中的各取代基的定義與說明書中的定義相同。