A toilet flush lever sanitizing device is provided. The device may include a housing to contain internal components. The present invention further includes a sensor operable to detect a motion of the toilet lever of the toilet. A pressurized sanitizer canister that contains a sanitizer is disposed within the housing. The canister includes a nozzle that is directed towards the toilet lever. When the sensor detects the motion of the toilet lever, the sanitizer canister delivers a spray of sanitizer from the nozzle after a period of time from the detection of the motion.