PROBLEM TO BE SOLVED: To provide a modified peptide of human acidic fibroblast growth factor (aFGF), and to provide a pharmaceutical composition containing the peptide and a pharmaceutically acceptable carrier.SOLUTION: A modified peptide of human acidic fibroblast growth factor (aFGF) comprises a native human aFGF shortened by a deletion of 20 amino acids from the N-terminal of the native human aFGF, and an alanine (Ala) added before the shortened native aFGF. A pharmaceutical composition contains the isolated peptide and a pharmaceutically acceptable carrier.COPYRIGHT: (C)2015,JPO&INPIT【課題】ヒト酸性繊維芽細胞増殖因子(aFGF)の改変ペプチド、前記ペプチド及び医薬上許容し得る担体を含む医薬組成物を提供する。【解決手段】ヒト酸性繊維芽細胞増殖因子(aFGF)の改変ペプチドであって、ネイティブなヒトaFGFのN末端から20個のアミノ酸を欠失させることにより短化したネイティブヒトaFGF、および該短化ネイティブaFGFの前に付加されたアラニン(Ala)を含む、ペプチド。前記単離ペプチド及び医薬上許容し得る担体を含む、医薬組成物。【選択図】なし
