Guidewire retainers for use with catheters and related methods and kits are disclosed. According to an aspect, a guidewire retainer includes a body that defines an interior space therein and an opening at one end that provides passage from an exterior of the body to the interior space. The interior space can be shaped and sized for holding an end of a guidewire. The guidewire retainer also includes a locking mechanism configured to close the body for attaching the body to the end of the guidewire.
