MACDONALD, Lynn,MURPHY, Andrew,MCWHIRTER, John,TU, Naxin,VORONINA, Vera,GURER, Cagan,MEAGHER, Karolina,STEVENS, Sean
申请号:
ES12784833
公开号:
ES2691475T3
申请日:
2012.10.26
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
#$%^&*AU2012327204A120130523.pdf#####ABSTRACT The invention provides a genetically modified non-human animal that comprises in its genome unrearranged T cell receptor variable gene loci, as well as embryos, cells, and tissues comprising the same. Also provided are constructs for making said genetically modified non-human animal and methods of making the same. Various methods of using the genetically modified non-human animal are also provided.