ARMANDO DI TEODORO,WERNER HOELZL,DIETER REINEHR,RUDOLF ZINK
申请号：
BR0110458
公开号：
BR0110458B1
申请日:
2001.04.26
申请国别(地区):
BR
年份:
2012
代理人:
摘要：
There is described a process for the preparation of halogenated hydroxydiphenyl compounds of formula (1) by acylation of a halogenated benzene compound (first stage), etherification of the acylated compound with a halogenated phenol compound, which is not further substituted in the ortho-position (second stage), oxidation of the etherified compound (third stage) and hydrolysis of the oxidized compound in a fourth stage, wherein the reaction of the second stage is carried out in the presence of K2CO3 and any desired copper catalyst, where K2CO3 is used in a concentration of from 0.5 to 30 mol, based on the phenol compound employed of formula (6), according to the reaction scheme (I) in which R1 and R2 independently of one another are F, Cl or Br； R3 and R4 independently of one another are hydrogen； or C1-C4alkyl； m is 1 to 3； and n is 1 or 2. The compounds of formula (1) are used for protecting organic materials and articles from microorganisms.
