THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA
发明人:
TWETEN, RODNEY K.
申请号:
EP11174235
公开号:
EP2386567A3
申请日:
2008.04.14
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Mutants of cholesterol-dependent cytolysins comprising at least one amino acid substitution in at least one of Loop 1, Loop 2, or Loop 3 of Domain 4, nucleic acids encoding such polypeptide mutants, and compositions and vaccines comprising such polypeptide mutants.