A syringe includes a barrel having an internal surface defining an internal bore therein； a plunger having a distal end disposed within the internal bore of the barrel, and a proximal end disposed outside the internal bore of the barrel； and a dose divider configured to bear on the barrel in response to translation of the plunger relative to the barrel along the longitudinal direction. The dose divider includes a base including a flange that extends at least partly in a radial direction； and at least one column extending away from the base along the longitudinal direction. The at least one column includes a proximal end and a distal end opposite the proximal end, the proximal end of the at least one column being coupled to the base. The at least one column includes a sacrificial portion coupled to a frangible link.
