PROTÉINE DE LIAISON À L'ANTIGÈNE RECONNAISSANT UN PEPTIDE DÉRIVÉ D'UN MAGE-A4

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专利权人:

Mie University

发明人:

申请号：

EP18813904.2

公开号：

EP3636761A1

申请日:

2018.06.05

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

[Problem] To provide CAR-T cells that can be used in CAR infusion therapy wherein a cancer-specific intracellular antigen is used.[Solution] The problem is solved by CAR-T cells for cancer therapy provided with an antibody that recognizes the MAGE-A4-derived-peptide/HLA-A2 complex, wherein the antibody has VH amino acid sequence of SEQ ID NO: 36 and VL amino acid sequence of SEQ ID NO: 38. In the case, the antibody preferably is provided with the amino acid sequence of SEQ ID NO: 32.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/