Henricus Leo Bernardus Maria Klaasen,Peter Loeffen,Eric Onno Rijke
申请号:
US14420944
公开号:
US09375480B2
申请日:
2013.08.16
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention pertains to a composition containing an immunogenic cell preparation of killed Leptospira bacteria in a citric acid solution. It also pertains to a vaccine to protect an animal against an infection with Leptospira bacteria, wherein the vaccine comprises this composition, and to the use of citric acid to stabilize an immunogenic preparation of killed Leptospira bacteria in a liquid carrier, by dissolving the citric acid in the carrier.